Despite the great advances in medical research, biofilm-associated infections are still regarded as a serious complication. In implant medicine, bacterial colonization of foreign material surfaces can cause severe inflammation. These infections are thought to be a principle reason for implant function loss and usually require costly surgical interventions that are stressful to the patient. To improve the clinical situation, the BIOFABRICATION project aims to develop and optimize innovative implant surfaces that are specifically functionalized to fight biofilm infections and/or completely abolish microbial adherence.