We present a time-resolved photographic analysis of the pulse-to-pulse interaction of temporally separated fs-laser pulses with various pulse overlap in water. Initially, by decreasing the temporal separation of laser pulses there is a diminishment of the laser-induced optical breakdown (LIOB) probability, caused by focusing into persisting gas bubbles at the focal volume. A LIOB at the focal spot is finally impaired by the oscillating cavitation bubble of the preceding pulse. Hence, the interaction between the laser and transparent ophthalmic tissue may be accompanied by a raised laser energy transmission and a variation in the axial cutting depth, which could be observed in case of a pulse overlap. In conclusion, our experimental results are of particular importance for the optimization of the prospective ophthalmic surgical process with future-generation fs-lasers.