U. Oberheide
B. Jansen
I. Bruder
H. Lubatschowski
H. Welling

Optoacoustical tissue differentiation for on-line therapy control

Optical Biopsy and Tissue Optics
5.-6. Juli
Amsterdam
2000
Type: Konferenzbeitrag
Abstract
In this work, the localization of the ciliary body region of porcine eyes with laser optoacoustics was realized. The principle of laser optoacoustics combines the advantages of ultrasound and optical tomography. The absorption of short laser pulses in the near infrared generates thermoelastic stress waves in the ciliary muscle and the underlying pigmented epithelial layers. These stress transients were detected at the surface of the sclera with piezoelectric transducers in order to analyze the structure. The optoacoustical measurements of the ciliary body region at different positions from the corneoscleral limbus were composed to a grayscale image, which could be qualitatively compared to histological sections of this region. In these images the pigmented layers can be localized. The influence of the detectional wavelength on the optoacoustical signal in the NIR between 750 and 1052 nm was investigated. Furthermore, changes in the optoacoustic signal due to coagulation with a diode laser using typical therapeutical parameters could be observed.