B. Matthias
T. Ripken
A. Krüger

Dispersion Encoded Full Range Fourier Domain Optical Coherence Tomography for Image-Guidance of Fs-Laser Lens Surgery

Biomedical Engineering / Biomedizinische Technik
S1
59
S560-S563
2014
Type: Zeitschriftenaufsatz (reviewed)
Abstract
Fs-laser surgery is an emerging technique for cutting of the crystalline lens, e.g. in assisting cataract surgery and for presbyopia treatment through lentotomy. An intraoperative depth resolved imaging is required for precise targeting the nucleus and cortex while keeping of safety distance to the capsule. Spectrometer based Fourier domain optical coherence tomography (OCT) at 840 nm is customized for a 1040 nm fs-laser surgical system in order to guide focus positioning in the anterior eye. The OCT sample beam and the fs-laser beam share the same scanner and focusing optics. Conventionally, FD-OCT images suffer from disturbing mirror artifacts due to an complex ambiguity processing the real-valued measured spectral signal. We make use of the dispersion encoded full range (DEFR) algorithm to suppress these complex conjugate artifacts exploiting a dispersion mismatch between sample and reference arm and thereby increase the usable imaging range. The C++ implemented processing and display is performed in real time on the graphics processing unit. The developed spectrometer provides a single-sided measurement range in air of 11.96 mm at average axial resolution of 14.6 μm. The -3dB-limit of the spectrometer is 2 mm and sensitivity decreases further with about -3.3dB/mm. By means of DEFR mirror artifacts in the OCT images are suppressed and imaging the whole anterior segment of porcine eye is demonstrated. Based on the obtained image information subsequent surgical procedures can be defined. Utilizing DEFR technique reduces complexity of FD-OCT-guided fs-laser surgery systems and increases system stability. Moving and error-prone parts for artifact suppression and image depth extension are unnecessary. Costly hardware, such as phase shifting elements, can be spared. Real-time visualization is a critical characteristic in image-guided laser surgery and provides competitive advantages in the market.