This paper describes the monolithic series connection of organic thin-film solar modules by means of laser structuring. Experiments are performed with a broad range of laser sources and parameters. The most important laser parameters in thin film processing are the radiation wavelength, pulse duration, pulse energy and spot-to-spot overlap. Processing with several wavelengths (e.g. 355 nm, 532 nm, and 1064 nm) and pulse durations in the femto-, pico- and nanosecond ranges are evaluated. The results obtained with the best suitable laser sources are further optimized and presented in this paper. The focus of the experiments is to obtain an optimal edge quality without damaging the substrate or the layer below the structured region. Organic test cells on glass substrates are produced using the optimized laser structuring process. These are analysed and have an efficiency comparable to cells structured with methods, commonly used in research laboratories. The presented results, show the applicability of the technology for future mass production where processing speeds greater than 1m/s are required. Currently available industrial laser sources are able to achieve these processing speeds, necessary for economically feasible structuring of organic modules in a roll-to-roll production.